Francisco Bezanilla

Biosciences Graduate Program Association
  1. Catacuzzeno L, Franciolini F, Bezanilla F, Eisenberg RS. Gating current noise produced by Brownian models of a voltage sensor. Biophys J. 2021 Sep 21; 120(18):3983-4001. View in: PubMed

  2. Bassetto CA, Carvalho-de-Souza JL, Bezanilla F. Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K+ channels. Elife. 2021 Feb 23; 10. View in: PubMed

  3. Moreno C, Yano S, Bezanilla F, Latorre R, Holmgren M. Transient Electrical Currents Mediated by the Na+/K+-ATPase: A Tour from Basic Biophysics to Human Diseases. Biophys J. 2020 07 21; 119(2):236-242. View in: PubMed

  4. Rastogi SK, Garg R, Scopelliti MG, Pinto BI, Hartung JE, Kim S, Murphey CGE, Johnson N, San Roman D, Bezanilla F, Cahoon JF, Gold MS, Chamanzar M, Cohen-Karni T. Remote nongenetic optical modulation of neuronal activity using fuzzy graphene. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13339-13349. View in: PubMed

  5. Du X, Carvalho-de-Souza JL, Wei C, Carrasquel-Ursulaez W, Lorenzo Y, Gonzalez N, Kubota T, Staisch J, Hain T, Petrossian N, Xu M, Latorre R, Bezanilla F, Gomez CM. Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6023-6034. View in: PubMed

  6. Bassetto CAZ, Carvalho-de-Souza JL, Bezanilla F. Metal Bridge in S4 Segment Supports Helix Transition in Shaker Channel. Biophys J. 2020 02 25; 118(4):922-933. View in: PubMed

  7. Carvalho-de-Souza JL, Bezanilla F. Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker. Nat Commun. 2019 08 08; 10(1):3584. View in: PubMed

  8. Acarón Ledesma H, Li X, Carvalho-de-Souza JL, Wei W, Bezanilla F, Tian B. An atlas of nano-enabled neural interfaces. Nat Nanotechnol. 2019 07; 14(7):645-657. View in: PubMed

  9. Jiang Y, Parameswaran R, Li X, Carvalho-de-Souza JL, Gao X, Meng L, Bezanilla F, Shepherd GMG, Tian B. Nongenetic optical neuromodulation with silicon-based materials. Nat Protoc. 2019 05; 14(5):1339-1376. View in: PubMed

  10. Horng TL, Eisenberg RS, Liu C, Bezanilla F. Continuum Gating Current Models Computed with Consistent Interactions. Biophys J. 2019 01 22; 116(2):270-282. View in: PubMed

  11. Lee EEL, Bezanilla F. Methodological improvements for fluorescence recordings in Xenopus laevis oocytes. J Gen Physiol. 2019 02 04; 151(2):264-272. View in: PubMed

  12. Carvalho-de-Souza JL, Nag OK, Oh E, Huston AL, Vurgaftman I, Pepperberg DR, Bezanilla F, Delehanty JB. Cholesterol Functionalization of Gold Nanoparticles Enhances Photoactivation of Neural Activity. ACS Chem Neurosci. 2019 03 20; 10(3):1478-1487. View in: PubMed

  13. Bezanilla F. Influences: The Cell Physiology Laboratory in Montemar, Chile. J Gen Physiol. 2018 11 05; 150(11):1464-1468. View in: PubMed

  14. Bezanilla F. Gating currents. J Gen Physiol. 2018 07 02; 150(7):911-932. View in: PubMed

  15. Infield DT, Lee EEL, Galpin JD, Galles GD, Bezanilla F, Ahern CA. Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape. J Gen Physiol. 2018 07 02; 150(7):1017-1024. View in: PubMed

  16. Carrasquel-Ursulaez W, Alvarez O, Bezanilla F, Latorre R. Determination of the Stoichiometry between a- and ?1 Subunits of the BK Channel Using LRET. Biophys J. 2018 06 05; 114(11):2493-2497. View in: PubMed

  17. Parameswaran R, Carvalho-de-Souza JL, Jiang Y, Burke MJ, Zimmerman JF, Koehler K, Phillips AW, Yi J, Adams EJ, Bezanilla F, Tian B. Photoelectrochemical modulation of neuronal activity with free-standing coaxial silicon nanowires. Nat Nanotechnol. 2018 03; 13(3):260-266. View in: PubMed

  18. Mathur C, Johnson KR, Tong BA, Miranda P, Srikumar D, Basilio D, Latorre R, Bezanilla F, Holmgren M. Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation. Sci Rep. 2018 02 02; 8(1):2207. View in: PubMed

  19. Brugarolas P, Sánchez-Rodríguez JE, Tsai HM, Basuli F, Cheng SH, Zhang X, Caprariello AV, Lacroix JJ, Freifelder R, Murali D, DeJesus O, Miller RH, Swenson RE, Chen CT, Herscovitch P, Reich DS, Bezanilla F, Popko B. Development of a PET radioligand for potassium channels to image CNS demyelination. Sci Rep. 2018 01 12; 8(1):607. View in: PubMed

  20. Carvalho-de-Souza JL, Bezanilla F. Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels. J Gen Physiol. 2018 02 05; 150(2):307-321. View in: PubMed

  21. Nanazashvili M, Sánchez-Rodríguez JE, Fosque B, Bezanilla F, Sackin H. LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b. Biophys J. 2018 01 09; 114(1):88-97. View in: PubMed

  22. Carvalho-de-Souza JL, Pinto BI, Pepperberg DR, Bezanilla F. Optocapacitive Generation of Action Potentials by Microsecond Laser Pulses of Nanojoule Energy. Biophys J. 2018 01 23; 114(2):283-288. View in: PubMed

  23. Tian B, Xu S, Rogers JA, Cestellos-Blanco S, Yang P, Carvalho-de-Souza JL, Bezanilla F, Liu J, Bao Z, Hjort M, Cao Y, Melosh N, Lanzani G, Benfenati F, Galli G, Gygi F, Kautz R, Gorodetsky AA, Kim SS, Lu TK, Anikeeva P, Cifra M, Krivosudský O, Havelka D, Jiang Y. Roadmap on semiconductor-cell biointerfaces. Phys Biol. 2018 03 09; 15(3):031002. View in: PubMed

  24. Kubota T, Dang B, Carvalho-de-Souza JL, Correa AM, Bezanilla F. Nav channel binder containing a specific conjugation-site based on a low toxicity ß-scorpion toxin. Sci Rep. 2017 11 27; 7(1):16329. View in: PubMed

  25. Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F. Correspondence: Reply to 'Revisiting the theoretical cell membrane thermal capacitance response'. Nat Commun. 2017 11 10; 8(1):1432. View in: PubMed

  26. Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F. Corrigendum: Infrared light excites cells by changing their electrical capacitance. Nat Commun. 2017 11 10; 8:16148. View in: PubMed

  27. Lee EEL, Bezanilla F. Biophysical Characterization of Genetically Encoded Voltage Sensor ASAP1: Dynamic Range Improvement. Biophys J. 2017 Nov 21; 113(10):2178-2181. View in: PubMed

  28. Kubota T, Correa AM, Bezanilla F. Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit. Sci Rep. 2017 03 28; 7:45310. View in: PubMed

  29. Kubota T, Durek T, Dang B, Finol-Urdaneta RK, Craik DJ, Kent SB, French RJ, Bezanilla F, Correa AM. Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proc Natl Acad Sci U S A. 2017 03 07; 114(10):E1857-E1865. View in: PubMed

  30. Dang B, Shen R, Kubota T, Mandal K, Bezanilla F, Roux B, Kent SB. Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew Chem Int Ed Engl. 2017 03 13; 56(12):3324-3328. View in: PubMed

  31. Barchad-Avitzur O, Priest MF, Dekel N, Bezanilla F, Parnas H, Ben-Chaim Y. A Novel Voltage Sensor in the Orthosteric Binding Site of the M2 Muscarinic Receptor. Biophys J. 2016 Oct 04; 111(7):1396-1408. View in: PubMed

  32. Jiang Y, Carvalho-de-Souza JL, Wong RC, Luo Z, Isheim D, Zuo X, Nicholls AW, Jung IW, Yue J, Liu DJ, Wang Y, De Andrade V, Xiao X, Navrazhnykh L, Weiss DE, Wu X, Seidman DN, Bezanilla F, Tian B. Heterogeneous silicon mesostructures for lipid-supported bioelectric interfaces. Nat Mater. 2016 09; 15(9):1023-30. View in: PubMed

  33. Dang B, Kubota T, Mandal K, Correa AM, Bezanilla F, Kent SB. Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angew Chem Int Ed Engl. 2016 07 18; 55(30):8639-42. View in: PubMed

  34. Castillo JP, Sánchez-Rodríguez JE, Hyde HC, Zaelzer CA, Aguayo D, Sepúlveda RV, Luk LY, Kent SB, Gonzalez-Nilo FD, Bezanilla F, Latorre R. ß1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel. Proc Natl Acad Sci U S A. 2016 Jun 07; 113(23):E3231-9. View in: PubMed

  35. Labro AJ, Priest MF, Lacroix JJ, Snyders DJ, Bezanilla F. Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization. Nat Commun. 2015 Dec 17; 6:10173. View in: PubMed

  36. Treger JS, Priest MF, Bezanilla F. Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator. Elife. 2015 Nov 24; 4:e10482. View in: PubMed

  37. Li Q, Shen R, Treger JS, Wanderling SS, Milewski W, Siwowska K, Bezanilla F, Perozo E. Resting state of the human proton channel dimer in a lipid bilayer. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E5926-35. View in: PubMed

  38. Priest M, Bezanilla F. Functional Site-Directed Fluorometry. Adv Exp Med Biol. 2015; 869:55-76. View in: PubMed

  39. Castillo JP, Rui H, Basilio D, Das A, Roux B, Latorre R, Bezanilla F, Holmgren M. Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase. Nat Commun. 2015 Jul 24; 6:7622. View in: PubMed

  40. Carvalho-de-Souza JL, Treger JS, Dang B, Kent SB, Pepperberg DR, Bezanilla F. Photosensitivity of neurons enabled by cell-targeted gold nanoparticles. Neuron. 2015 Apr 08; 86(1):207-17. View in: PubMed

  41. Sánchez-Rodríguez JE, Khalili-Araghi F, Miranda P, Roux B, Holmgren M, Bezanilla F. A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway. J Mol Biol. 2015 Mar 27; 427(6 Pt B):1335-1344. View in: PubMed

  42. Treger JS, Priest MF, Iezzi R, Bezanilla F. Real-time imaging of electrical signals with an infrared FDA-approved dye. Biophys J. 2014 Sep 16; 107(6):L09-12. View in: PubMed

  43. Kubota T, Lacroix JJ, Bezanilla F, Correa AM. Probing a-3(10) transitions in a voltage-sensing S4 helix. Biophys J. 2014 Sep 02; 107(5):1117-1128. View in: PubMed

  44. Dang B, Kubota T, Correa AM, Bezanilla F, Kent SB. Total chemical synthesis of biologically active fluorescent dye-labeled Ts1 toxin. Angew Chem Int Ed Engl. 2014 Aug 18; 53(34):8970-4. View in: PubMed

  45. Lacroix JJ, Hyde HC, Campos FV, Bezanilla F. Moving gating charges through the gating pore in a Kv channel voltage sensor. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):E1950-9. View in: PubMed

  46. Dalmas O, Sompornpisut P, Bezanilla F, Perozo E. Molecular mechanism of Mg2+-dependent gating in CorA. Nat Commun. 2014 Apr 02; 5:3590. View in: PubMed

  47. Dalmas O, Sandtner W, Medovoy D, Frezza L, Bezanilla F, Perozo E. A repulsion mechanism explains magnesium permeation and selectivity in CorA. Proc Natl Acad Sci U S A. 2014 Feb 25; 111(8):3002-7. View in: PubMed

  48. Priest MF, Lacroix JJ, Villalba-Galea CA, Bezanilla F. S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel. Biophys J. 2013 Nov 19; 105(10):2312-22. View in: PubMed

  49. Bezanilla F, Villalba-Galea CA. The gating charge should not be estimated by fitting a two-state model to a Q-V curve. J Gen Physiol. 2013 Dec; 142(6):575-8. View in: PubMed

  50. Villalba-Galea CA, Frezza L, Sandtner W, Bezanilla F. Sensing charges of the Ciona intestinalis voltage-sensing phosphatase. J Gen Physiol. 2013 Nov; 142(5):543-55. View in: PubMed

  51. Lacroix JJ, Campos FV, Frezza L, Bezanilla F. Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation. Neuron. 2013 Aug 21; 79(4):651-7. View in: PubMed

  52. Dang B, Kubota T, Mandal K, Bezanilla F, Kent SB. Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography. J Am Chem Soc. 2013 Aug 14; 135(32):11911-9. View in: PubMed

  53. Capes DL, Goldschen-Ohm MP, Arcisio-Miranda M, Bezanilla F, Chanda B. Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels. J Gen Physiol. 2013 Aug; 142(2):101-12. View in: PubMed

  54. Shapiro MG, Priest MF, Siegel PH, Bezanilla F. Thermal mechanisms of millimeter wave stimulation of excitable cells. Biophys J. 2013 Jun 18; 104(12):2622-8. View in: PubMed

  55. Ruscic KJ, Miceli F, Villalba-Galea CA, Dai H, Mishina Y, Bezanilla F, Goldstein SA. IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):E559-66. View in: PubMed

  56. Lacroix JJ, Pless SA, Maragliano L, Campos FV, Galpin JD, Ahern CA, Roux B, Bezanilla F. Intermediate state trapping of a voltage sensor. J Gen Physiol. 2012 Dec; 140(6):635-52. View in: PubMed

  57. Vargas E, Yarov-Yarovoy V, Khalili-Araghi F, Catterall WA, Klein ML, Tarek M, Lindahl E, Schulten K, Perozo E, Bezanilla F, Roux B. An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. J Gen Physiol. 2012 Dec; 140(6):587-94. View in: PubMed

  58. Labro AJ, Lacroix JJ, Villalba-Galea CA, Snyders DJ, Bezanilla F. Molecular mechanism for depolarization-induced modulation of Kv channel closure. J Gen Physiol. 2012 Nov; 140(5):481-93. View in: PubMed

  59. Hyde HC, Sandtner W, Vargas E, Dagcan AT, Robertson JL, Roux B, Correa AM, Bezanilla F. Nano-positioning system for structural analysis of functional homomeric proteins in multiple conformations. Structure. 2012 Oct 10; 20(10):1629-40. View in: PubMed

  60. Lacroix JJ, Bezanilla F. Tuning the voltage-sensor motion with a single residue. Biophys J. 2012 Aug 08; 103(3):L23-L25. View in: PubMed

  61. Miceli F, Vargas E, Bezanilla F, Taglialatela M. Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain. Biophys J. 2012 Mar 21; 102(6):1372-82. View in: PubMed

  62. Shapiro MG, Homma K, Villarreal S, Richter CP, Bezanilla F. Infrared light excites cells by changing their electrical capacitance. Nat Commun. 2012 Mar 13; 3:736. View in: PubMed

  63. Gadsby DC, Bezanilla F, Rakowski RF, De Weer P, Holmgren M. The dynamic relationships between the three events that release individual Na? ions from the Na?/K?-ATPase. Nat Commun. 2012 Feb 14; 3:669. View in: PubMed

  64. Dekel N, Priest MF, Parnas H, Parnas I, Bezanilla F. Depolarization induces a conformational change in the binding site region of the M2 muscarinic receptor. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):285-90. View in: PubMed

  65. Vargas E, Bezanilla F, Roux B. In search of a consensus model of the resting state of a voltage-sensing domain. Neuron. 2011 Dec 08; 72(5):713-20. View in: PubMed

  66. Castillo JP, De Giorgis D, Basilio D, Gadsby DC, Rosenthal JJ, Latorre R, Holmgren M, Bezanilla F. Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20556-61. View in: PubMed

  67. Sandtner W, Egwolf B, Khalili-Araghi F, Sánchez-Rodríguez JE, Roux B, Bezanilla F, Holmgren M. Ouabain binding site in a functioning Na+/K+ ATPase. J Biol Chem. 2011 Nov 04; 286(44):38177-38183. View in: PubMed

  68. Lacroix JJ, Bezanilla F. Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6444-9. View in: PubMed

  69. Lacroix J, Halaszovich CR, Schreiber DN, Leitner MG, Bezanilla F, Oliver D, Villalba-Galea CA. Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential. J Biol Chem. 2011 May 20; 286(20):17945-53. View in: PubMed

  70. Lacroix JJ, Labro AJ, Bezanilla F. Properties of deactivation gating currents in Shaker channels. Biophys J. 2011 Mar 02; 100(5):L28-30. View in: PubMed

  71. Gagnon DG, Bezanilla F. The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers. J Gen Physiol. 2010 Nov; 136(5):555-68. View in: PubMed

  72. Miceli F, Cilio MR, Taglialatela M, Bezanilla F. Gating currents from neuronal K(V)7.4 channels: general features and correlation with the ionic conductance. Channels (Austin). 2009 Jul-Aug; 3(4):274-83. View in: PubMed

  73. Villalba-Galea CA, Miceli F, Taglialatela M, Bezanilla F. Coupling between the voltage-sensing and phosphatase domains of Ci-VSP. J Gen Physiol. 2009 Jul; 134(1):5-14. View in: PubMed

  74. Gagnon DG, Bezanilla F. A single charged voltage sensor is capable of gating the Shaker K+ channel. J Gen Physiol. 2009 May; 133(5):467-83. View in: PubMed

  75. Rosenthal JJ, Seibel BA, Dymowska A, Bezanilla F. Trade-off between aerobic capacity and locomotor capability in an Antarctic pteropod. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6192-6. View in: PubMed

  76. Villalba-Galea CA, Sandtner W, Dimitrov D, Mutoh H, Knöpfel T, Bezanilla F. Charge movement of a voltage-sensitive fluorescent protein. Biophys J. 2009 Jan; 96(2):L19-21. View in: PubMed

  77. Blunck R, McGuire H, Hyde HC, Bezanilla F. Fluorescence detection of the movement of single KcsA subunits reveals cooperativity. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20263-8. View in: PubMed

  78. Bezanilla F. Ion channels: from conductance to structure. Neuron. 2008 Nov 06; 60(3):456-68. View in: PubMed

  79. Villalba-Galea CA, Sandtner W, Starace DM, Bezanilla F. S4-based voltage sensors have three major conformations. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17600-7. View in: PubMed

  80. Campos FV, Chanda B, Beirão PS, Bezanilla F. Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels. J Gen Physiol. 2008 Aug; 132(2):251-63. View in: PubMed

  81. Bezanilla F. How membrane proteins sense voltage. Nat Rev Mol Cell Biol. 2008 Apr; 9(4):323-32. View in: PubMed

  82. Chanda B, Bezanilla F. A common pathway for charge transport through voltage-sensing domains. Neuron. 2008 Feb 07; 57(3):345-51. View in: PubMed

  83. Sandtner W, Bezanilla F, Correa AM. In vivo measurement of intramolecular distances using genetically encoded reporters. Biophys J. 2007 Nov 01; 93(9):L45-7. View in: PubMed

  84. Campos FV, Chanda B, Beirão PS, Bezanilla F. beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel. J Gen Physiol. 2007 Sep; 130(3):257-68. View in: PubMed

  85. Campos FV, Chanda B, Roux B, Bezanilla F. Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel. Proc Natl Acad Sci U S A. 2007 May 08; 104(19):7904-9. View in: PubMed

  86. Bezanilla F. The action potential: from voltage-gated conductances to molecular structures. Biol Res. 2006; 39(3):425-35. View in: PubMed

  87. Ben-Chaim Y, Chanda B, Dascal N, Bezanilla F, Parnas I, Parnas H. Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor. Nature. 2006 Nov 02; 444(7115):106-9. View in: PubMed

  88. Richardson J, Blunck R, Ge P, Selvin PR, Bezanilla F, Papazian DM, Correa AM. Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer. Proc Natl Acad Sci U S A. 2006 Oct 24; 103(43):15865-70. View in: PubMed

  89. Blunck R, Cordero-Morales JF, Cuello LG, Perozo E, Bezanilla F. Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. J Gen Physiol. 2006 Nov; 128(5):569-81. View in: PubMed

  90. Jurisic N, Bezanilla F. Analysis of the optimal channel density of the squid giant axon using a reparameterized Hodgkin-Huxley model. J Neurophysiol. 2006 Aug; 96(2):959; author reply 960. View in: PubMed

  91. Bannister JP, Chanda B, Bezanilla F, Papazian DM. Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor. Proc Natl Acad Sci U S A. 2005 Dec 20; 102(51):18718-23. View in: PubMed

  92. Chanda B, Blunck R, Faria LC, Schweizer FE, Mody I, Bezanilla F. A hybrid approach to measuring electrical activity in genetically specified neurons. Nat Neurosci. 2005 Nov; 8(11):1619-26. View in: PubMed

  93. Chanda B, Asamoah OK, Blunck R, Roux B, Bezanilla F. Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement. Nature. 2005 Aug 11; 436(7052):852-6. View in: PubMed

  94. Posson DJ, Ge P, Miller C, Bezanilla F, Selvin PR. Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer. Nature. 2005 Aug 11; 436(7052):848-51. View in: PubMed

  95. Bezanilla F. The origin of subconductance levels in voltage-gated K+ channels. J Gen Physiol. 2005 Aug; 126(2):83-6. View in: PubMed

  96. Bezanilla F. The voltage-sensor structure in a voltage-gated channel. Trends Biochem Sci. 2005 Apr; 30(4):166-8. View in: PubMed

  97. Bezanilla F. Voltage-gated ion channels. IEEE Trans Nanobioscience. 2005 Mar; 4(1):34-48. View in: PubMed

  98. Loo DD, Hirayama BA, Cha A, Bezanilla F, Wright EM. Perturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter. J Gen Physiol. 2005 Jan; 125(1):13-36. View in: PubMed

  99. Pantoja R, Nagarah JM, Starace DM, Melosh NA, Blunck R, Bezanilla F, Heath JR. Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics. Biosens Bioelectron. 2004 Oct 15; 20(3):509-17. View in: PubMed

  100. Bezanilla F. RNA editing of a human potassium channel modifies its inactivation. Nat Struct Mol Biol. 2004 Oct; 11(10):915-6. View in: PubMed

  101. Kuzmenkin A, Bezanilla F, Correa AM. Gating of the bacterial sodium channel, NaChBac: voltage-dependent charge movement and gating currents. J Gen Physiol. 2004 Oct; 124(4):349-56. View in: PubMed

  102. Dahan DS, Dibas MI, Petersson EJ, Auyeung VC, Chanda B, Bezanilla F, Dougherty DA, Lester HA. A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10195-200. View in: PubMed

  103. Blunck R, Starace DM, Correa AM, Bezanilla F. Detecting rearrangements of shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells. Biophys J. 2004 Jun; 86(6):3966-80. View in: PubMed

  104. Chanda B, Asamoah OK, Bezanilla F. Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements. J Gen Physiol. 2004 Mar; 123(3):217-30. View in: PubMed

  105. Starace DM, Bezanilla F. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature. 2004 Feb 05; 427(6974):548-53. View in: PubMed

  106. Sigg D, Bezanilla F, Stefani E. Fast gating in the Shaker K+ channel and the energy landscape of activation. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7611-5. View in: PubMed

  107. Sigg D, Bezanilla F. A physical model of potassium channel activation: from energy landscape to gating kinetics. Biophys J. 2003 Jun; 84(6):3703-16. View in: PubMed

  108. Bezanilla F, Perozo E. The voltage sensor and the gate in ion channels. Adv Protein Chem. 2003; 63:211-41. View in: PubMed

  109. Asamoah OK, Wuskell JP, Loew LM, Bezanilla F. A fluorometric approach to local electric field measurements in a voltage-gated ion channel. Neuron. 2003 Jan 09; 37(1):85-97. View in: PubMed

  110. Bezanilla F, Perozo E. Structural biology. Force and voltage sensors in one structure. Science. 2002 Nov 22; 298(5598):1562-3. View in: PubMed

  111. Chanda B, Bezanilla F. Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation. J Gen Physiol. 2002 Nov; 120(5):629-45. View in: PubMed

  112. Bezanilla F. Voltage sensor movements. J Gen Physiol. 2002 Oct; 120(4):465-73. View in: PubMed

  113. Rosenthal JJ, Bezanilla F. Extensive editing of mRNAs for the squid delayed rectifier K+ channel regulates subunit tetramerization. Neuron. 2002 May 30; 34(5):743-57. View in: PubMed

  114. Rosenthal JJ, Bezanilla F. A comparison of propagated action potentials from tropical and temperate squid axons: different durations and conduction velocities correlate with ionic conductance levels. J Exp Biol. 2002 Jun; 205(Pt 12):1819-30. View in: PubMed

  115. Rakowski RF, Bezanilla F, De Weer P, Gadsby DC, Holmgren M, Wagg J. Charge translocation by the Na/K pump. Ann N Y Acad Sci. 1997 Nov 03; 834:231-43. View in: PubMed

  116. Armstrong CM, Bezanilla FM, Horowicz P. Twitches in the presence of ethylene glycol bis( -aminoethyl ether)-N,N'-tetracetic acid. Biochim Biophys Acta. 1972 Jun 23; 267(3):605-8. View in: PubMed