Axel Concepcion

Assistant Professor
Biosciences Graduate Program Association
Publications
  1. Cav?1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function. Nat Commun. 2022 04 19; 13(1):2033. View in: PubMed

  2. The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling. Nat Immunol. 2022 02; 23(2):287-302. View in: PubMed

  3. STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells. EMBO Mol Med. 2020 08 07; 12(8):e11592. View in: PubMed

  4. Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells. Sci Signal. 2020 02 18; 13(619). View in: PubMed

  5. Eye on ion channels in immune cells. Sci Signal. 2019 03 12; 12(572). View in: PubMed

  6. Targeting the anion exchanger 2 with specific peptides as a new therapeutic approach in B lymphoid neoplasms. Haematologica. 2018 06; 103(6):1065-1072. View in: PubMed

  7. Regulation of epithelial ion transport in exocrine glands by store-operated Ca2+ entry. Cell Calcium. 2017 05; 63:53-59. View in: PubMed

  8. Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function. J Clin Invest. 2016 11 01; 126(11):4303-4318. View in: PubMed

  9. Dental enamel cells express functional SOCE channels. Sci Rep. 2015 Oct 30; 5:15803. View in: PubMed

  10. CD8+ T cells undergo activation and programmed death-1 repression in the liver of aged Ae2a,b-/- mice favoring autoimmune cholangitis. Oncotarget. 2015 Oct 06; 6(30):28588-606. View in: PubMed

  11. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. J Immunol. 2015 Aug 01; 195(3):1202-17. View in: PubMed

  12. Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease. J Hepatol. 2015 Oct; 63(4):952-61. View in: PubMed

  13. Mouse models of primary biliary cirrhosis. Curr Pharm Des. 2015; 21(18):2401-13. View in: PubMed

  14. Anion exchanger 2 is critical for CD8(+) T?cells to maintain pHi homeostasis and modulate immune responses. Eur J Immunol. 2014 May; 44(5):1341-51. View in: PubMed

  15. Role of AE2 for pHi regulation in biliary epithelial cells. Front Physiol. 2013; 4:413. View in: PubMed

  16. Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice. Gut. 2013 Jun; 62(6):899-910. View in: PubMed

  17. Approaches to the pathogenesis of primary biliary cirrhosis through animal models. Clin Res Hepatol Gastroenterol. 2012 Feb; 36(1):21-8. View in: PubMed